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Article

CREB-mediated IL-6 expression is required for 15(S)-hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2009

Chava Koteswara R, Karpurapu Manjula, Wang Dong, Bhanoori Manjula, Kundumani-Sridharan Venkatesh, Zhang Qiuhua, Ichiki Toshihiro, Glasgow Wayne C, Rao Gadiparthi N

Abstract excerpt

OBJECTIVE: Migration of vascular smooth muscle cells (VSMCs) from media to intima is a key event in the pathophysiology of atherosclerosis and restenosis. The lipoxygenase products of polyunsaturated fatty acids (PUFA) were shown to play a role in these diseases. cAMP response element binding protein (CREB) has been implicated in the regulation of VSMC growth and motility in response to thrombin and angiotensin...

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Identifiers

PMID: 19342597
DOI: 10.1161/ATVBAHA.109.185777
PMCID: PMC2724759

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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