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Article

Hyperhomocysteinemia, intima-media thickness and C677T MTHFR gene polymorphism: a correlation study in patients with cognitive impairment.

Atherosclerosis - 1 Sept 2009

Gorgone Gaetano, Ursini Francesca, Altamura Claudia, Bressi Federica, Tombini Mario, Curcio Giuseppe, Chiovenda Paola, Squitti Rosanna, Silvestrini Mauro, Ientile Riccardo, Pisani Francesco, Rossini Paolo Maria, Vernieri Fabrizio

Abstract excerpt

OBJECTIVE: Intima-media thickness (IMT) seems associated with risk of Alzheimer disease (AD). Homocysteine (hcy) is a risk factor for vascular diseases and dementia. This study aimed at investigating the possible relationship among IMT, plasma hcy and C677T methylentetrahydrofolate reductase (MTHFR) polymorphism in relation to cognitive status. METHODS: Sixty-three patients with cognitive impairment and 64...

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Source

Identifiers

PMID: 19342053
DOI: 10.1016/j.atherosclerosis.2009.02.028

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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