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Article

Associations between homocysteine metabolism related SNPs and carotid intima-media thickness: a Chinese sib pair study.

Journal of thrombosis and thrombolysis - 1 Apr 2017

Sun Kexin, Song Jing, Liu Kuo, Fang Kai, Wang Ling, Wang Xueyin, Li Jing, Tang Xun, Wu Yiqun, Qin Xueying, Wu Tao, Gao Pei, Chen Dafang, Hu Yonghua

Abstract excerpt

Carotid intima-media thickness (CIMT) is a good surrogate for atherosclerosis. Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases. We aim to investigate the relationships between homocysteine (Hcy) related biochemical indexes and CIMT, the associations between Hcy related SNPs and CIMT, as well as the potential gene-gene interactions. The present study recruited full siblings (186...

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Share to Carotid Artery, Common

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Coronary Artery Disease

Share to Epistasis, Genetic

Share to Homocysteine

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Source

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Identifiers

PMID: 27822905
DOI: 10.1007/s11239-016-1449-x
PMCID: PMC5337241

Genes

CBS
BHMT
MTR
MTHFR
MTRR
SHMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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