Effects of isolation and inbreeding on human quantitative traits: an example of biochemical markers of hemostasis and inflammation.

doi:10.3378/1534-6617-80.5.513

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Effects of isolation and inbreeding on human quantitative traits: an example of biochemical markers of hemostasis and inflammation.

Human biology - 1 Oct 2008

Pulanić Drazen, Polasek Ozren, Petrovecki Mladen, Vorko-Jović Ariana, Pericić Marijana, Lauc Lovorka Barać, Klarić Irena Martinović, Biloglav Zrinka, Kolcić Ivana, Zgaga Lina, Carothers Andrew D, Ramić Senad, Setić Mia, Janićijević Branka, Narancić Nina Smolej, Bućan Kajo, Rudan Diana, Lowe Gordon, Rumley Ann, Rudan Pavao, Campbell Harry, Rudan Igor

Abstract excerpt

Isolation is a known force in evolutionary biology and one of the main factors in speciation. One of the main consequences of severe isolation is reduced mate choice, which results in the occurrence of inbreeding as a result of isolation. We investigated the effects of individual genome-wide heterozygosity measured as the multilocus heterozygosity (MLH) on biochemical markers of hemostasis and inflammation in...

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PMID: 19341321
DOI: 10.3378/1534-6617-80.5.513

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