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Article

Mitochondrial DNA haplogroups influence lipoatrophy after highly active antiretroviral therapy.

Journal of acquired immune deficiency syndromes (1999) - 1 Jun 2009

Hendrickson Sher L, Kingsley Lawrence A, Ruiz-Pesini Eduardo, Poole Jason C, Jacobson Lisa P, Palella Frank J, Bream Jay H, Wallace Douglas C, O'Brien Stephen J

Abstract excerpt

Although highly active antiretroviral therapy (HAART) has been extremely effective in lowering AIDS incidence among patients infected with HIV, certain drugs included in HAART can cause serious mitochondrial toxicities. One of the most frequent adverse events is lipoatrophy, which is the loss of subcutaneous fat in the face, arms, buttocks, and/or legs as an adverse reaction to nucleoside reverse transcriptase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19339895
DOI: 10.1097/QAI.0b013e3181a324d6
PMCID: PMC2742970

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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