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Mitochondrial DNA variation and changes in adiponectin and endothelial function in HIV-infected adults after antiretroviral therapy initiation.

AIDS research and human retroviruses - 1 Oct 2013

Hulgan Todd, Stein James H, Cotter Bruno R, Murdock Deborah G, Ritchie Marylyn D, Dube Michael P, Gerschenson Mariana, Haas David W, Torriani Francesca J

Abstract excerpt

Studies in persons of European descent have suggested that mitochondrial DNA (mtDNA) haplogroups influence antiretroviral therapy (ART) toxicity. We explored associations between mtDNA variants and changes in endothelial function and biomarkers among non-Hispanic white, ART-naive subjects starting ART. A5152s was a substudy of A5142, a randomized trial of initial class-sparing ART regimens that included efavirenz...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 23944767
DOI: 10.1089/aid.2013.0079
PMCID: PMC3785797

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