Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project.

doi:10.1158/0008-5472.CAN-08-2604

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Article

Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project.

Cancer research - 1 Apr 2009

Canova Cristina, Hashibe Mia, Simonato Lorenzo, Nelis Mari, Metspalu Andres, Lagiou Pagona, Trichopoulos Dimitrios, Ahrens Wolfgang, Pigeot Iris, Merletti Franco, Richiardi Lorenzo, Talamini Renato, Barzan Luigi, Macfarlane Gary J, Macfarlane Tatiana V, Holcátová Ivana, Bencko Vladimir, Benhamou Simone, Bouchardy Christine, Kjaerheim Kristina, Lowry Ray, Agudo Antonio, Castellsagué Xavier, Conway David I, McKinney Patricia A, Znaor Ariana, McCartan Bernard E, Healy Claire M, Marron Manuela, Brennan Paul

Abstract excerpt

Cancers of the upper aerodigestive tract (UADT) include malignant tumors of the oral cavity, pharynx, larynx, and esophagus and account for 6.4% of all new cancers in Europe. In the context of a multicenter case-control study conducted in 14 centers within 10 European countries and comprising 1,511 cases and 1,457 controls (ARCAGE study), 115 single nucleotide polymorphisms (SNP) from 62 a priori-selected genes...

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PMID: 19339270
DOI: 10.1158/0008-5472.CAN-08-2604

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