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Article

The association of sequence variants in DNA repair and cell cycle genes with cancers of the upper aerodigestive tract.

Carcinogenesis - 1 Mar 2007

Hall Janet, Hashibe Mia, Boffetta Paolo, Gaborieau Valerie, Moullan Norman, Chabrier Amelie, Zaridze David, Shangina Oxana, Szeszenia-Dabrowska Neonila, Mates Dana, Janout Vladimir, Fabiánová Eleonóra, Holcatova Ivana, Hung Rayjean J, McKay James, Canzian Federico, Brennan Paul

Abstract excerpt

Cancers of the upper aerodigestive tract (UADT), comprising the oral cavity, pharynx, larynx and oesophagus, account for 5.2% of all cancers cases worldwide. The major risk factors, tobacco and alcohol can directly or indirectly generate DNA damage, which if unrepaired can give rise to mutations,...

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Source

Identifiers

PMID: 17040931
DOI: 10.1093/carcin/bgl160

Genes

MGMT
CHEK2
OGG1
XPA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17040931-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The association of sequence variants in DNA repair and cell cycle genes with cancers of the upper aerodigestive tract.PMID 17040931Read ↗

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Alcohol-related cancers and genetic susceptibility in Europe: the ARCAGE project: study samples and data collection.Semantic proximity Read ↗

Genetic variants in DNA repair pathways and risk of upper aerodigestive tract cancers: combined analysis of data from two genome-wide association studies in European populations.Semantic proximity Read ↗

The associations of sequence variants in DNA-repair and cell-cycle genes with cancer risk: genotype-phenotype correlations.Semantic proximity Read ↗

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