Article
Heritable variation of ERBB2 and breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2009
Breyer Joan P, Sanders Melinda E, Airey David C, Cai Qiuyin, Yaspan Brian L, Schuyler Peggy A, Dai Qi, Boulos Fouad, Olivares Maria G, Bradley Kevin M, Gao Yu-Tang, Page David L, Dupont William D, Zheng Wei, Smith Jeffrey R
Abstract excerpt
Amplification of the epithelial growth factor receptor gene ERBB2 (HER2, NEU) in breast cancer is associated with a poor clinical prognosis. In mammary gland development, this receptor plays a role in ductal and lobuloalveolar differentiation. We conducted a systematic investigation of the role o...
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