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Article

Population-based, case-control study of HER2 genetic polymorphism and breast cancer risk.

Journal of the National Cancer Institute - 1 Mar 2000

Xie D, Shu X O, Deng Z, Wen W Q, Creek K E, Dai Q, Gao Y T, Jin F, Zheng W

Abstract excerpt

BACKGROUND: Alterations of the HER2 (also known as erbB-2 or neu) proto-oncogene have been implicated in the carcinogenesis and prognosis of breast cancer. A polymorphism at codon 655 (GTC/valine to ATC /isoleucine [Val(655)Ile]) in the transmembrane domain-coding region of this gene has been identified and may be associated with the risk of breast cancer. We evaluated this hypothesis in a subgroup of women who...

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PMID: 10699071
DOI: 10.1093/jnci/92.5.412

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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