Article
High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups.
Arthritis and rheumatism - 1 Apr 2009
Namjou Bahram, Sestak Andrea L, Armstrong Don L, Zidovetzki Raphael, Kelly Jennifer A, Jacob Noam, Ciobanu Voicu, Kaufman Kenneth M, Ojwang Joshua O, Ziegler Julie, Quismorio Francesco P, Reiff Andreas, Myones Barry L, Guthridge Joel M, Nath Swapan K, Bruner Gail R, Mehrian-Shai Ruth, Silverman Earl, Klein-Gitelman Marisa, McCurdy Deborah, Wagner-Weiner Linda, Nocton James J, Putterman Chaim, Bae Sang-Cheol, Kim Yun Jung, Petri Michelle, Reveille John D, Vyse Timothy J, Gilkeson Gary S, Kamen Diane L, Alarcón-Riquelme Marta E, Gaffney Patrick M, Moser Kathy L, Merrill Joan T, Scofield R Hal, James Judith A, Langefeld Carl D, Harley John B, Jacob Chaim O
Abstract excerpt
OBJECTIVE: Systemic lupus erythematosus (SLE) is the prototypical systemic autoimmune disorder, with complex etiology and a strong genetic component. Recently, gene products involved in the interferon pathway have been under intense investigation in terms of the pathogenesis of SLE. STAT-1 and ST...
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