Article
HLA-DR-DQ haplotypes and type 1 diabetes in Macedonia.
Human immunology - 1 Jun 2009
Ilonen Jorma, Kocova Mirjana, Lipponen Kati, Sukarova-Angelovska Elena, Jovanovska Aleksandra, Knip Mikael
Abstract excerpt
The lowest incidence of childhood type 1 diabetes in Europe has been reported from the Republic of Macedonia. To assess the possible genetic contribution we analyzed the distribution of HLA-DR-DQ haplotypes among 163 diabetic children and 239 healthy controls. Similar disease associations were found as in other Caucasian populations. HLA-(DR3)-DQA1*05-DQB1*02 was the most common disease associated haplotype, but...
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