Article
[HLA haplotypes in families with type 1 diabetes].
Revista medica de Chile - 1 Dec 1998
Pérez F, Santos J L, Calvillán M, Carrasco E
Abstract excerpt
BACKGROUND: Inherited susceptibility to type 1 diabetes is partially determined by HLA genes. HLA-DQA1 and DQB1 alleles have been chosen as the most sensitive susceptibility markers. Family studies are a good method to establish specific relationship between type 1 diabetes and specific haplotypes as risk markers for the disease. AIM: To analyse the role of class II HLA molecules and the distribution of...
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