Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effect of a promoter polymorphism on the transcription of nitric oxide synthase 1 and its relevance to Parkinson's disease.

Journal of neuroscience research - 1 Aug 2009

Rife Terrie, Rasoul Bareza, Pullen Nicholas, Mitchell David, Grathwol Kristen, Kurth Janice

Abstract excerpt

Transcriptional changes of the enzyme nitric oxide synthase I (NOS1) are believed to play a role in the development of many diseases. The gene for NOS1 has 12 alternative first exons (1A-1L). The 1F exon is one of the most highly utilized first exons in the brain and has a polymorphism ((TG)(m)TA(TG)(n)) located in its promoter region. The polymorphism's length has been suggested to affect NOS1 transcription and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HeLa Cells

Share to Nitric Oxide Synthase Type I

Share to Parkinson Disease

Share to Promoter Regions, Genetic

Share to Regulatory Sequences, Nucleic Acid

Share to Transfection

Source

Identifiers

PMID: 19326438
DOI: 10.1002/jnr.22045

Genes

NOS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effect of a promoter polymorphism on the transcription of nitric oxide synthase 1 and its relevance to Parkinson's disease.PMID 19326438Read ↗

Association of Polymorphism of Neuronal Nitric Oxide Synthase Gene with Risk to Parkinson's Disease.Semantic proximity Read ↗

DNA sequence analysis of monoamine oxidase B gene coding and promoter regions in Parkinson's disease cases and unrelated controls.Semantic proximity Read ↗

Microsatellite polymorphism in the human heme oxygenase-1 gene promoter and its application in association studies with Alzheimer and Parkinson disease.Semantic proximity Read ↗

5'-flanking region polymorphism of the neuronal nitric oxide synthase gene with Parkinson's disease in Taiwan.Semantic proximity Read ↗

Association of a NOS1 promoter repeat with Alzheimer's disease.Semantic proximity Read ↗

Genetic analysis of heme oxygenase-1 (HO-1) in German Parkinson's disease patients.Semantic proximity Read ↗

Genetic analysis of nitric oxide synthase 1 variants in schizophrenia and bipolar disorder.Semantic proximity Read ↗

Neuronal nitric oxide synthase C276T polymorphism increases the risk for frontotemporal lobar degeneration.Semantic proximity Read ↗

Comprehensive association analysis of the NOS2A gene with Parkinson disease.Semantic proximity Read ↗

A putative cis-acting polymorphism in the NOS1 gene is associated with schizophrenia and NOS1 immunoreactivity in the postmortem brain.Semantic proximity Read ↗

Association of a functional NOS1 promoter repeat with Alzheimer's disease in the VITA cohort.Semantic proximity Read ↗

Cloning and functional analysis of the allelic polymorphism in the transcription regulatory region of interleukin-1 alpha.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.