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Article

Association of a NOS1 promoter repeat with Alzheimer's disease.

Neurobiology of aging - 1 Sept 2008

Galimberti Daniela, Scarpini Elio, Venturelli Eliana, Strobel Alexander, Herterich Sabine, Fenoglio Chiara, Guidi Ilaria, Scalabrini Diego, Cortini Francesca, Bresolin Nereo, Lesch Klaus-Peter, Reif Andreas

Abstract excerpt

The gene encoding NOS-I (NOS1) displays a complex transcriptional regulation, with nine alternative first exons. Exon 1c and 1f are the most abundant forms in the brain. A functional single nucleotide polymorphism (SNP) in exon 1c and a polymorphism in exon 1f, consisting of a variable number of tandem repeats (VNTR) originating short (S) and long (L) alleles, were studied in 184 patients with Alzheimer's disease...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Genetic Predisposition to Disease

Share to Nitric Oxide Synthase Type I

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Share to Repetitive Sequences, Nucleic Acid

Source

Identifiers

PMID: 17418914
DOI: 10.1016/j.neurobiolaging.2007.03.003

Genes

NOS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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