Article
What can genetic variation tell us about the evolution of senescence?
Proceedings. Biological sciences - 22 Jun 2009
Moorad Jacob A, Promislow Daniel E L
Abstract excerpt
Quantitative genetic approaches have been developed that allow researchers to determine which of two mechanisms, mutation accumulation (MA) or antagonistic pleiotropy (AP), best explain observed variation in patterns of senescence using classical quantitative genetic techniques. These include the creation of mutation accumulation lines, artificial selection experiments and the partitioning of genetic variances...
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