Article
Testing evolutionary models of senescence: traditional approaches and future directions.
Human genetics - 1 Dec 2014
Robins Chloe, Conneely Karen N
Abstract excerpt
From an evolutionary perspective, the existence of senescence is a paradox. Why has senescence not been more effectively selected against given its associated decreases in Darwinian fitness? Why does senescence exist and how has it evolved? Three major theories offer explanations: (1) the theory of mutation accumulation suggested by PB Medawar; (2) the theory of antagonistic pleiotropy suggested by GC Williams;...
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