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Article

Age-specific inbreeding depression and components of genetic variance in relation to the evolution of senescence.

Proceedings of the National Academy of Sciences of the United States of America - 11 Jun 1996

Charlesworth B, Hughes K A

Abstract excerpt

Two major theories of the evolution of senescence (mutation accumulation and antagonistic pleiotropy) make different predictions about the relationships between age, inbreeding effects, and the magnitude of genetic variance components of life-history components. We show that, under mutation accumulation, inbreeding decline and three major components of genetic variance are expected to increase with age in...

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Identifiers

PMID: 8650233
DOI: 10.1073/pnas.93.12.6140
PMCID: PMC39203

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