Article
E-Cadherin regulates neural stem cell self-renewal.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 25 Mar 2009
Karpowicz Phillip, Willaime-Morawek Sandrine, Balenci Laurent, DeVeale Brian, Inoue Tomoyuki, van der Kooy Derek
Abstract excerpt
E-Cadherin, a cell adhesion protein, has been shown to take part in the compartmentalization, proliferation, survival, and differentiation of cells. E-Cadherin is expressed in the adult and embryonic forebrain germinal zones in vivo, and in clonal colonies of cells derived from these regions and grown in vitro. Mice carrying E-Cadherin floxed genes crossed to mice expressing Cre under the Nestin promoter...
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