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Article

Regulation of Histone Deposition on the Herpes Simplex Virus Type 1 Genome during Lytic Infection

26 Mar 2009

Abstract excerpt

During lytic infection by herpes simplex virus type 1 (HSV-1), histones are present at relatively low levels on the viral genome. However, the mechanisms that account for such low levels--how histone deposition on the viral genome is blocked or how histones are removed from the genome--are not yet defined. In this study, we show that histone occupancy on the viral genome gradually increased with time when...

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PMID: 19321615
DOI: 10.1128/jvi.00219-09

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