Article
Association of tumor necrosis factor gene polymorphisms with susceptibility to dilated cardiomyopathy in a Han Chinese population.
DNA and cell biology - 1 Oct 2010
Liang Wei-Bo, Lv Mei-Li, Su Xiao-Wei, Gao Lin-Bo, Fang Wen-Liang, Luo Hai-Bo, Zhang Lin
Abstract excerpt
Tumor necrosis factor (TNF) is an immunomodulatory cytokine that plays an important role in many inflammatory and autoimmune diseases. We investigated the correlation between single-nucleotide polymorphisms of the TNF gene [i.e., TNF-α (308), TNF-α (857), TNF-α (863), TNF-α (1031), and TNF-ß (+252)] and dilated cardiomyopathy (DCM). A total of 110 DCM patients and 110 control subjects were genotyped using...
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