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Article

Genetic association of IL-21 polymorphisms with dilated cardiomyopathy in a Han Chinese population.

Herz - 1 May 2015

Lin J, Peng Y, Zhou B, Dou Q, Li Y, Yang H, Zhang L, Rao L

Abstract excerpt

BACKGROUND: Autoimmune abnormalities appear to be major predisposing factors for dilated cardiomyopathy (DCM). Interleukin-21 (IL-21) gene polymorphisms have been previously found to be associated with autoimmune diseases. This study aimed to assess the role of IL-21 in DCM in a Han Chinese population. PATIENTS AND METHODS: A total of 364 independent DCM patients and 384 unrelated healthy controls were recruited...

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PMID: 24445858
DOI: 10.1007/s00059-013-4039-0

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