Article
Variant FCGR3 genes: transcription and possible origins.
Asian Pacific journal of allergy and immunology - 1 Dec 2008
Tong Yin, Jin Jie, Marget Matthias, Humpe Andreas, Neppert Juergen, Flesch Brigitte K
Abstract excerpt
The Fc receptors for human immunoglobulin G (FcgammaR) IIIb are encoded by genes clustered on the long arm of chromosome 1 (band q21 --> 24) and exhibit allelic polymorphisms. Several rare FCGR3B sequences were identified in both white and black donors. However, the origins of these genomic variants are unknown and their transcription has not yet been investigated. Blood from a donor with known FCGR3 variants was...
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