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Article

Evidence for gene recombination in FCGR3 gene variants.

Vox sanguinis - 1 Jul 2009

Blum K S, Tong Y, Siebert R, Marget M, Humpe A, Neppert J, Flesch B K

Abstract excerpt

BACKGROUND AND OBJECTIVES: The genes encoding the Fcgamma receptors (FcgammaR) IIIa and IIIb (FCGR3A and FCGR3B) are clustered on chromosome 1 band q23-24 and exhibit allelic polymorphism. We investigated the molecular basis of additional new FCGR3 genomic variation. MATERIALS AND METHODS: A segment shared by FCGR3A and FCGR3B containing the polymorphic nucleotide positions 141, 147, 227, 266, and 277 in exon 3...

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Share to Chromosomes, Human, Pair 1
Share to Cloning, Molecular
Share to GPI-Linked Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Receptors, IgG

Share to Recombination, Genetic

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 19320901
DOI: 10.1111/j.1423-0410.2009.01178.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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