Article
FCGR3B*03 allele inheritance pattern in Brazilian families and some new variants of gene FCGR3B.
Transfusion - 1 Mar 2012
Terzian Claudia C N, Chiba Akemi K, Santos Viviani C, Silva Neusa P, Bordin Jose O
Abstract excerpt
BACKGROUND: The FCGR3B gene encoding the FcyRIIIb receptor for immunoglobulin G has three polymorphic forms known as HNA-1a, HNA-1b, and HNA-1c, encoded by the alleles FCGR3B*01, FCGR3B*02, and FCGR3B*03, respectively. It is not clear whether the inheritance of the FCGR3B*03 allele, which encodes the HNA-1c, is linked or not to the other two alleles. The objective of this study was to identify the inheritance...
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