Polymorphisms in oxidative drug metabolism: relationship to food preference.

doi:10.1111/j.1365-2125.1991.tb03887.x

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Article

Polymorphisms in oxidative drug metabolism: relationship to food preference.

British journal of clinical pharmacology - 1 Aug 1991

Britto M R, McKean H E, Bruckner G G, Wedlund P J

Abstract excerpt

To determine whether a correlation exists between polymorphisms of oxidative drug metabolism and dietary preference, 29 poor metabolizers of dextromethorphan, 18 poor metabolizers of mephenytoin and 134 extensive metabolizers of both drugs were screened for their preferences for various food items. Poor metabolizers of dextromethorphan showed a diminished stated preference for cauliflower and coconut, and poor...

Topics

Adult
Cytochrome P-450 Enzyme System
Dextromethorphan
Food Preferences
Humans
Male
Mephenytoin
Oxidation-Reduction
Pharmaceutical Preparations
Phenotype
Polymorphism, Genetic

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