Article
ICAM-1 (Lys469Glu) and PECAM-1 (Leu125Val) polymorphisms in diffuse astrocytomas.
Clinical and experimental medicine - 1 Jun 2009
Burim Regislaine Valéria, Teixeira Silvia Aparecida, Colli Benedicto Oscar, Peria Fernanda Maris, Tirapelli Luis Fernando, Marie Suely Kazue Nagahashi, Malheiros Suzana Maria Fleury, Oba-Shinjo Sueli Mieko, Gabbai Alberto Alain, Lotufo Paulo Andrade, Carlotti-Júnior Carlos Gilberto
Abstract excerpt
Cell adhesion molecules such as intercellular adhesion molecule-1 (ICAM-1) and platelet-endothelial cell adhesion molecule-1 (PECAM-1) play an important role in glioma invasion and angiogenesis. The aim of this study was to investigate whether specific genetic polymorphisms of ICAM-1 and PECAM-1 could be associated with glioma development and progression. Single-nucleotide polymorphism in codon 469 of ICAM-1 and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.