Article
Human leukocyte antigen frequency in human high-grade gliomas: a case-control study in Sicily.
Neurosurgery - 1 Jun 2009
La Torre Domenico, Maugeri Rosario, Angileri Filippo F, Pezzino Gaetana, Conti Alfredo, Cardali Salvatore M, Calisto Amedeo, Sciarrone Giuseppe, Misefari Aldo, Germanò Antonino, Tomasello Francesco
Abstract excerpt
OBJECTIVE: Human leukocyte antigens (HLAs) are widely expressed cell surface molecules that present antigenic peptides to T lymphocytes and modulate immune response against inflammatory and malignant diseases. The aim of this study was to compare HLA distribution in patients with newly diagnosed high-grade gliomas (HGGs) and 2 control groups from a restricted geographic area (eastern Sicily). METHODS: HLA allele...
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