Article
Human leukocyte antigen distribution analysis in North Italian brain Glioma patients: an association with HLA-DRB1*14.
Journal of neuro-oncology - 1 Apr 2006
Guerini Franca R, Agliardi Cristina, Zanzottera Milena, Delbue Serena, Pagani Elisabetta, Tinelli Carmine, Boldorini Renzo, Car Pier Giorgio, Veggiani Claudia, Ferrante Pasquale
Abstract excerpt
Human leukocyte antigens (HLA) are widely expressed cell surface molecules that present antigenic peptides to T-lymphocytes and modulate the immune response against inflammatory and malignant disease. Frequently, tumoral cells express antigens that are recognized by the immune system. Ineffective immune response could be the result of defects in antigen presentation in those subjects with peculiar HLA alleles,...
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