Article
Platelet-endothelial cell adhesion molecule-1 gene polymorphism and its soluble level are associated with ischemic stroke.
DNA and cell biology - 1 Mar 2009
Wei Ye-Sheng, Lan Yan, Liu Yun-Guang, Meng Lan-Qing, Xu Qun-Qing, Xie Hai-Yuan
Abstract excerpt
Inflammation, characterized by the recruitment and adhesion of circulating leukocytes by cellular adhesion molecules, plays an important role in the pathogenesis of atherosclerosis. Genetic analyses of platelet-endothelial cell adhesion molecule-1 (PECAM-1), a key adhesion molecule in the progression of atherosclerosis, have provided conflicting results regarding the role of variation within the PECAM-1 gene and...
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