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Article

The centrosomal FOP protein is required for cell cycle progression and survival.

Cell cycle (Georgetown, Tex.) - 15 Apr 2009

Acquaviva Claire, Chevrier Véronique, Chauvin Jean-Paul, Fournier Gaëlle, Birnbaum Daniel, Rosnet Olivier

Abstract excerpt

FOP is a centrosomal protein originally discovered as a fusion partner of FGFR1 in patients with a rare stem cell myeloproliferative disorder. In DT40 chicken lymphocytes, we show that the normal FOP protein localizes at the centrosome throughout the cell cycle and preferentially accumulates at t...

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Source

Identifiers

PMID: 19305129
DOI: 10.4161/cc.8.8.8248

Genes

FAS
FGFR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19305129-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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