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Article

Multidrug resistance gene deficient ( <i>mdr1a</i> <sup>-/-</sup> ) mice have an altered caecal microbiota that precedes the onset of intestinal inflammation

3 Mar 2009

Abstract excerpt

AIM: To compare caecal microbiota from mdr1a(-/-) and wild type (FVB) mice to identify differences in the bacterial community that could influence the intestinal inflammation. METHODS AND RESULTS: Caecal microbiota of mdr1a(-/-) and FVB mice were evaluated at 12 and 25 weeks of age using denaturing gradient gel electrophoresis (DGGE) and quantitative real-time PCR. DGGE fingerprints of FVB and mdr1a(-/-) mice...

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PMID: 19302324
DOI: 10.1111/j.1365-2672.2009.04225.x

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