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Article

Emergent genome-wide control in wildtype and genetically mutated lipopolysaccarides-stimulated macrophages.

PloS one - 1 Jan 2009

Tsuchiya Masa, Piras Vincent, Choi Sangdun, Akira Shizuo, Tomita Masaru, Giuliani Alessandro, Selvarajoo Kumar

Abstract excerpt

Large-scale gene expression studies have mainly focused on highly expressed and 'discriminatory' genes to decipher key regulatory processes. Biological responses are consequence of the concerted action of gene regulatory network, thus, limiting our attention to genes having the most significant variations is insufficient for a thorough understanding of emergent whole genome response. Here we comprehensively...

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Identifiers

PMID: 19300509
DOI: 10.1371/journal.pone.0004905
PMCID: PMC2654147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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