Article
Pleiotropy and GAL pathway degeneration in yeast.
Journal of evolutionary biology - 1 Jul 2007
MacLean R C
Abstract excerpt
Traits that do not contribute to fitness are expected to be lost during the course of evolution, either as a result of selection or drift. The Leloir pathway of galactose metabolism (GAL) is an extensively studied metabolic pathway that degenerated on at least three independent occasions during the evolutionary diversification of yeasts, suggesting that the pathway is costly to maintain in environments that lack...
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