Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11.

Development (Cambridge, England) - 1 May 2009

Kawauchi Shimako, Kim Joon, Santos Rosaysela, Wu Hsiao-Huei, Lander Arthur D, Calof Anne L

Abstract excerpt

Foxg1, a winged-helix transcription factor, promotes the development of anterior neural structures; in mice lacking Foxg1, development of the cerebral hemispheres and olfactory epithelium (OE) is severely reduced. It has been suggested that Foxg1 acts by positively regulating the expression of growth factors, such as Fgf8, which support neurogenesis. However, Foxg1 also binds Smad transcriptional complexes,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Morphogenetic Proteins
Share to Cerebral Cortex
Share to Cyclin-Dependent Kinase Inhibitor p21

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelium

Share to Fibroblast Growth Factor 8

Share to Nasal Mucosa

Share to Neurogenesis

Share to Olfactory Bulb

Source

Open in PubMed Open full text

Identifiers

PMID: 19297409
DOI: 10.1242/dev.034967
PMCID: PMC2674256

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11.PMID 19297409Read ↗

GDF11 expressed in the adult brain negatively regulates hippocampal neurogenesisSemantic proximity Read ↗

Initiation of olfactory placode development and neurogenesis is blocked in mice lacking both Six1 and Six4.Semantic proximity Read ↗

Canonical Wnt signaling modulates <i>Tbx1</i>, <i>Eya1</i>, and <i>Six1</i> expression, restricting neurogenesis in the otic vesicleSemantic proximity Read ↗

Fgf8 expression defines a morphogenetic center required for olfactory neurogenesis and nasal cavity development in the mouse.Semantic proximity Read ↗

Foxd1 is required for proper formation of the optic chiasm.Semantic proximity Read ↗

Morphogenesis is transcriptionally coupled to neurogenesis during peripheral olfactory organ development.Semantic proximity Read ↗

LHX2 is necessary for the maintenance of optic identity and for the progression of optic morphogenesis.Semantic proximity Read ↗

Ebf1 controls early cell differentiation in the embryonic striatum.Semantic proximity Read ↗

Bone morphogenic protein signaling is a major determinant of dentate development.Semantic proximity Read ↗

Synergistic interaction between Gdf1 and Nodal during anterior axis development.Semantic proximity Read ↗

TGFβ-facilitated optic fissure fusion and the role of bone morphogenetic protein antagonismSemantic proximity Read ↗

Sox2 and Pou2f1 interact to control lens and olfactory placode development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.