Temporal switching and cell-to-cell variability in Ca2+ release activity in mammalian cells.

Abstract excerpt

Genetically identical cells in a uniform external environment can exhibit different phenotypes, which are often masked by conventional measurements that average over cell populations. Although most studies on this topic have used microorganisms, differentiated mammalian cells have rarely been explored. Here, we report that only approximately 40% of clonal human embryonic kidney 293 cells respond with an...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Caffeine
• Share to Calcium
• Share to Cell Cycle