Article
Prepatterning in the stem cell compartment.
PloS one - 28 May 2010
Tonge Peter D, Olariu Victor, Coca Daniel, Kadirkamanathan Visakan, Burrell Kelly E, Billings Stephen A, Andrews Peter W
Abstract excerpt
The mechanism by which an apparently uniform population of cells can generate a heterogeneous population of differentiated derivatives is a fundamental aspect of pluripotent and multipotent stem cell behaviour. One possibility is that the environment and the differentiation cues to which the cells are exposed are not uniform. An alternative, but not mutually exclusive possibility is that the observed...
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