Article
Analysis association between mitochondrial genome instability and xenobiotic metabolizing genes in human breast cancer.
Molecular medicine (Cambridge, Mass.) - 1 Jan 2000
Pavicic Walter H, Laguens Martin, Richard Silvina M
Abstract excerpt
The aim of this study was to determine the existence of association between the genetic polymorphisms of metabolizing genes GSTM-1, GSTT-1, and NAT-2, and the presence of mitochondrial genome instability (mtGI) in breast cancer cases. Ninety-four pairs of tumoral/nontumoral breast cancer samples were analyzed. Our samples showed 40.42% of mtGI by analysis of two D-loop region markers, a (CA)n mtMS starting at the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
