Article
Adult-onset degeneration of adipose tissue in mice deficient for the Sox8 transcription factor.
Journal of lipid research - 1 Jul 2009
Guth Sabine I E, Schmidt Katy, Hess Andreas, Wegner Michael
Abstract excerpt
Although the transcription factor Sox8 is broadly expressed during embryogenesis in developing ectodermal and mesodermal tissues, mice develop surprisingly normally in the absence of Sox8. Phenotypes in adult Sox8-deficient mice include mild osteopenia, late-onset male infertility, and reduced we...
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