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Article

MRAP mediated adipocyte differentiation by thymic MSCs contributes to thymic adipose involution

2022-06-01

Abstract excerpt

<title>Abstract</title> <p>Adipocyte deposition is believed to be a primary characteristic of age-related thymic involution, but the underlying cellular and molecular mechanisms remain unknown. We show here that thymic mesenchymal stromal cells (tMSCs) are differentiated into adipocytes through melanocortin-2 receptor accessory protein (MRAP). Specifically, we found that in contrast to bone-forming MSCs isolated...

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Identifiers and source

Literature Corpus work
8507c86b-fadb-5a16-99f5-2c8ed89d28e9
DOI
10.21203/rs.3.rs-1680754/v1
Open publication

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MRAP mediated adipocyte differentiation by thymic MSCs contributes to thymic adipose involutionDOI 10.21203/rs.3.rs-1680754/v1
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