Article
Down-regulation of Sox11 is required for efficient osteogenic differentiation of adipose-derived stem cells.
Molecules and cells - 1 Apr 2014
Choi Mi Kyung, Seong Ikjoo, Kang Seon Ah, Kim Jaesang
Abstract excerpt
Adipose-derived stem cells represent a type of mesenchymal stem cells with the attendant capacity to self-renew and differentiate into multiple cell lineages. We have performed a microarray-based gene expression profiling of osteogenic differentiation and found that the transcription factor Sox11 is down-regulated during the process. Functional assays demonstrate that down-regulation of Sox11 is required for an...
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