Article
Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice.
Diabetologia - 1 Apr 2018
Xia Jonathan Y, Sun Kai, Hepler Chelsea, Ghaben Alexandra L, Gupta Rana K, An Yu A, Holland William L, Morley Thomas S, Adams Andrew C, Gordillo Ruth, Kusminski Christine M, Scherer Philipp E
Abstract excerpt
AIM/HYPOTHESIS: Adiponectin (APN), a circulating hormone secreted by mature adipocytes, has been extensively studied because it has beneficial metabolic effects. While many studies have focused on the congenital loss of APN and its effects on systemic body glucose and lipid metabolism, little is known about the effects triggered by acute loss of APN in the adult mouse. We anticipated that genetically induced...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.