Article

Loss of FSTL1-expressing adipocyte progenitors drives the age-related involution of brown adipose tissue

2020-05-16

Abstract excerpt

<h4>SUMMARY</h4> In humans, brown adipose tissue (BAT) undergoes progressive involution or atrophy with increasing age, as manifested by decreased prevalence and mass, transformation to white adipose tissue (WAT), and reduction in thermogenic activity. This involution process cannot be fully recapitulated in rodent models and thus underlying cellular mechanisms are poorly understood. Here, we show that the inters...

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Identifiers and source

Literature Corpus work: 4338ba90-fa83-50eb-9522-784df758238e
DOI: 10.1101/2020.05.14.096990

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