Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Idiopathic weight reduction in mice deficient in the high-mobility-group transcription factor Sox8.

Molecular and cellular biology - 1 Oct 2001

Sock E, Schmidt K, Hermanns-Borgmeyer I, Bösl M R, Wegner M

Abstract excerpt

Sox8, Sox9, and Sox10 constitute subgroup E within the Sox family of transcription factors. Many Sox proteins are essential regulators of development. Sox9, for instance, is required for chondrogenesis and male sex determination; Sox10 plays key roles in neural crest development and peripheral gliogenesis. The function of Sox8 has not been studied so far. Here, we generated mice deficient in this third member of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Galactosidase
Share to Body Weight
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Embryo, Mammalian

Share to Genetic Vectors

Share to Mutagenesis

Share to SOXE Transcription Factors

Share to Tissue Distribution

Source

Open in PubMed Open full text

Identifiers

PMID: 11564878
DOI: 10.1128/MCB.21.20.6951-6959.2001
PMCID: PMC99871

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Idiopathic weight reduction in mice deficient in the high-mobility-group transcription factor Sox8.PMID 11564878Read ↗

Adult-onset degeneration of adipose tissue in mice deficient for the Sox8 transcription factor.Semantic proximity Read ↗

SoxE proteins are differentially required in mouse adrenal gland development.Semantic proximity Read ↗

<i>Sox9</i> in Testis DeterminationSemantic proximity Read ↗

Mouse model reveals the role of SOX7 in the development of congenital diaphragmatic hernia associated with recurrent deletions of 8p23.1Semantic proximity Read ↗

Variants in the SOX9 transactivation middle domain induce axial skeleton dysplasia and scoliosisSemantic proximity Read ↗

Generation of mice with a novel conditional null allele of the Sox9 gene.Semantic proximity Read ↗

Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence.Semantic proximity Read ↗

Heterozygous deletion of Sox9 in mouse mimics the gonadal sex reversal phenotype associated with campomelic dysplasia in humans.Semantic proximity Read ↗

Gene targeting reveals a widespread role for the high-mobility-group transcription factor Sox11 in tissue remodeling.Semantic proximity Read ↗

Generation of mice harboring a Sox4 conditional null allele.Semantic proximity Read ↗

Genome-wide identification of Sox8-, and Sox9-dependent genes during early post-natal testis development in the mouse.Semantic proximity Read ↗

Strain-Dependent Functional Variation of a Sex Specific Sox9 Enhancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.