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Article

Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways.

Hearing research - 1 Jul 2009

Owens Kelly N, Coffin Allison B, Hong Lisa S, Bennett Keri O'Connell, Rubel Edwin W, Raible David W

Abstract excerpt

We report a series of experiments investigating the kinetics of hair cell loss in lateral line neuromasts of zebrafish larvae following exposure to aminoglycoside antibiotics. Comparisons of the rate of hair cell loss and the differential effects of acute versus chronic exposure to gentamicin and neomycin revealed markedly different results. Neomycin induced rapid and dramatic concentration-dependent hair cell...

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Identifiers

PMID: 19285126
DOI: 10.1016/j.heares.2009.03.001
PMCID: PMC3167481

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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