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Article

Aminoglycoside ototoxicity.

Current opinion in otolaryngology & head and neck surgery - 1 Oct 2007

Rizzi Mark Douglas, Hirose Keiko

Abstract excerpt

PURPOSE OF REVIEW: To summarize mechanisms of ototoxicity associated with aminoglycoside antibiotics and discuss possible protective strategies. RECENT FINDINGS: Studies in the past 15 years have demonstrated that aminoglycoside ototoxicity is mediated by an apoptotic form of cell death which employs caspase-dependent pathways. Reactive oxygen species have been demonstrated in the sensory epithelium after...

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Identifiers

PMID: 17823553
DOI: 10.1097/MOO.0b013e3282ef772d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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