Article
Cilia-Associated Genes Play Differing Roles in Aminoglycoside-Induced Hair Cell Death in Zebrafish.
G3 (Bethesda, Md.) - 7 Jul 2016
Stawicki Tamara M, Hernandez Liana, Esterberg Robert, Linbo Tor, Owens Kelly N, Shah Arish N, Thapa Nihal, Roberts Brock, Moens Cecilia B, Rubel Edwin W, Raible David W
Abstract excerpt
Hair cells possess a single primary cilium, called the kinocilium, early in development. While the kinocilium is lost in auditory hair cells of most species it is maintained in vestibular hair cells. It has generally been believed that the primary role of the kinocilium and cilia-associated genes in hair cells is in the establishment of the polarity of actin-based stereocilia, the hair cell mechanotransduction...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.