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Functional SNPs in the SCGB3A2 promoter are associated with susceptibility to Graves' disease.

Human molecular genetics - 15 Mar 2009

Song Huai-Dong, Liang Jun, Shi Jing-Yi, Zhao Shuang-Xia, Liu Zhi, Zhao Jia-Jun, Peng Yong-De, Gao Guan-Qi, Tao Jiong, Pan Chun-Ming, Shao Li, Cheng Feng, Wang Yi, Yuan Guo-Yue, Xu Chao, Han Bing, Huang Wei, Chu Xun, Chen Yi, Sheng Yan, Li Rong-Ying, Su Qing, Gao Ling, Jia Wei-Ping, Jin Li, Chen Ming-Dao, Chen Sai-Juan, Chen Zhu, Chen Jia-Lun

Abstract excerpt

Graves' disease (GD) is one of the most common human autoimmune diseases, and recent data estimated a prevalence of clinical hyperthyroidism of 0.25-1.09% in the population. Several reports have linked GD to the region 5q12-q33; and a locus between markers D5s436 and D5s434 was specifically linked to GD susceptibility in the Chinese population. In the present study, association analysis was performed using a...

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PMID: 19126779
DOI: 10.1093/hmg/ddn442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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