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Article

Identification of conformational epitopes for human IgG on Chemotaxis inhibitory protein of Staphylococcus aureus.

BMC immunology - 11 Mar 2009

Gustafsson Erika, Haas Pieter-Jan, Walse Björn, Hijnen Marcel, Furebring Christina, Ohlin Mats, van Strijp Jos A G, van Kessel Kok P M

Abstract excerpt

BACKGROUND: The Chemotaxis inhibitory protein of Staphylococcus aureus (CHIPS) blocks the Complement fragment C5a receptor (C5aR) and formylated peptide receptor (FPR) and is thereby a potent inhibitor of neutrophil chemotaxis and activation of inflammatory responses. The majority of the healthy human population has antibodies against CHIPS that have been shown to interfere with its function in vitro. The aim of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19284584
DOI: 10.1186/1471-2172-10-13
PMCID: PMC2662796

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