Back to search

Article

Antibodies to Coagulase of <i>Staphylococcus aureus</i> crossreact to Efb and reveal different binding of shared Fibrinogen binding repeats

2022-04-04

Abstract excerpt

Staphylococcus aureus pathology is caused by a plethora of virulence factors able to combat multiple host defence mechanisms. Fibrinogen (Fg), a critical component in the host coagulation cascade, plays an important role in the pathogenesis of this bacterium, as it is the target of multiple staphylococcal virulence proteins. Amongst its secreted virulence factors, Coagulase (Coa) and Extracellular fibrinogen-bindi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
beff7b41-0a02-50b9-9ac7-91333f2987b3
DOI
10.1101/2022.04.01.486801
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Antibodies to Coagulase of <i>Staphylococcus aureus</i> crossreact to Efb and reveal different binding of shared Fibrinogen binding repeatsDOI 10.1101/2022.04.01.486801
Coagulase and Efb of Staphylococcus aureus Have a Common Fibrinogen Binding MotifSemantic proximity
Staphylococcus aureus interactions with the endotheliumSemantic proximity
Staphylococcal fibronectin-binding proteinsSemantic proximity
vhp Is a Fibrinogen-Binding Protein Related to vWbp in Staphylococcus aureusSemantic proximity
Dual-mode ClfA-targeting DARPin biologics protect against diverse methicillin-resistant <i>Staphylococcus aureus</i> strainsSemantic proximity
Surface shaving as a versatile tool to profile global interactions between human serum proteins and the Staphylococcus aureus cell surfaceSemantic proximity
Crystal structure of a <i>Staphylococcus aureus</i> protein A domain complexed with the Fab fragment of a human IgM antibody: Structural basis for recognition of B-cell receptors and superantigen activitySemantic proximity
A Fibrinogen-Binding Protein of <i>Staphylococcus epidermidis</i>Semantic proximity
Novel Staphylococcal Glycosyltransferases SdgA and SdgB Mediate Immunogenicity and Protection of Virulence-Associated Cell Wall ProteinsSemantic proximity
Five birds, one stone: Neutralization of α-hemolysin and 4 bi-component leukocidins of <i>Staphylococcus aureus</i> with a single human monoclonal antibodySemantic proximity
Coagulases as Determinants of Protective Immune Responses against Staphylococcus aureusSemantic proximity
Crystal structures of fibronectin-binding sites from <i>Staphylococcus aureus</i> FnBPA in complex with fibronectin domainsSemantic proximity
Select a neighboring publication to make it the new centre.